RNAinterference Identifies Genes Important for Cilia Structure and Function
File(s)
Date
2012-04Author
Braunreiter, Kara
Gabrhel, Casey
Advisor(s)
Lyman Gingerich, Jamie S.
Metadata
Show full item recordAbstract
Primary cilia are cellular antennae that mediate responses to the external environment. Response requires perception of a cue and transmission of that signal to the cell. This study employed a reverse genetic strategy known as RNAinterference to systematically reduce the function of each gene chromosome I and examine the effects on PKD-2 localization in C. elegans. Once the genes have been identified that affect PKD-2 localization, the role of these genes in cilia structure and function will be examined.
Subject
RNA
Genes--Identification
Cilia and ciliary motion
Posters
Permanent Link
http://digital.library.wisc.edu/1793/61839Description
Color poster with text, images, and charts.