Threat posed by multi-drug resistant staphylococcus aureus and possible new treatment options
Abstract
Staphylococcus aureus is a common commensal inhabitant of human mucus membranes and skin. Despite its role as a commensal, S. aureus also cause a wide range of infections in patients of all health backgrounds. Throughout the years, multi-drug resistant strains, often referred to as methicillin-resistant S. aureus (MRSA), have increased in prevalence and successful treatment is quite complicated. Even more disconcerting, development of new antimicrobials to combat rising infection rates/resistance rates has been slow. This review provides a general discussion of the evolution of MRSA, mechanisms of resistance to antimicrobial agents, current antimicrobials available for combating infection with MRSA, and future prospects for more effective treatment regimens.
Subject
Drug resistance in microorganisms.
Methicillin-Resistant Staphylococcus aureus -- United States.
Methicillin resistance.
Staphylococcus aureus infections.