An optimization approach for radiosurgery treatment planning
Abstract
We outline a new approach for radiosurgery treatment planning, based
on solving a series of optimization problems. We consider a speci c treat-
ment planning problem for a specialized device known as the Gamma
Knife, that provides an advanced stereotactic approach to the treatment
of tumors, vascular malformations, and pain disorders within the head.
The sequence of optimization problems involves nonlinear and mixed inte-
ger programs whose solution is required in a given planning time (typically
less than 30 minutes). This paper outlines several modeling decisions that
result in more e cient and robust solution. Furthermore, it outlines a
new approach for determining starting points for the nonlinear programs,
based on a skeletonization of the target volume. Treatment plans are
generated for real patient data that show the e ciency of the approach.
Subject
nonlinear programs
Gamma Knife
Permanent Link
http://digital.library.wisc.edu/1793/64314Citation
01-12